Type 2 allergic disorders uniquely identified within pediatric primary immunodeficiencies as novel co-existing masqueraders

Type 2 immunity (T2), described by high IgE/eosinophils (hIgEe) and allergy, is not an expected primary immunodeficiencies (PI) phenotype outside of syndromes of Hyper IgE, Wiskott, Atypical DiGeorge or Omenn. We uncovered T2 allergic disease novel to four different PIs affecting phagocytes; B cells; thymus/T-cells.
Source: Annals of Allergy, Asthma and Immunology - Category: Allergy & Immunology Authors: Tags: M364 Source Type: research