Molecular mechanisms for bone resorption by gingipains: Degradation of osteoprotegerin by lysine-specific gingipain is a key factor for enhanced osteoclastogenesis

Conclusion Our data suggests that degradation of OPG by Kgp is a crucial event in the progression of osteolysis in periodontitis.
Source: Journal of Oral Biosciences - Category: Biomedical Science Source Type: research