Interspecific variation of olfactory preferences in flies, mice, and humans.

Interspecific variation of olfactory preferences in flies, mice, and humans. Chem Senses. 2018 Nov 15;: Authors: Manoel D, Makhlouf M, Scialdone A, Saraiva LR Abstract Aiming to unravel interspecific differences in olfactory preferences, we performed comparative studies of odor valence in flies, mice, and humans. Our analysis suggests a model where flies and mice share similar olfactory preferences, but neither species share odor preferences with humans. This model contrasts with a previous study by Mandairon and colleagues, which suggested that the olfactory preferences of mice and humans are similar. A probabilistic examination revealed that underpowered studies can result in spurious significant correlations, which can account for the differences between both studies. Future analyses aimed at dissecting the olfactory preferences across species need to test large numbers of odorants in order to stress-test the model proposed here and identify robust associations. PMID: 30445540 [PubMed - as supplied by publisher]
Source: Chemical Senses - Category: Biochemistry Authors: Tags: Chem Senses Source Type: research