Exome sequencing of sporadic childhood ‐onset schizophrenia suggests the contribution of X‐linked genes in males

In conclusion, this article suggests that X ‐linked genes might play a role in the pathophysiology of COS. Candidate genes detailed here could explain the higher level of comorbidities and the earlier age of onset observed in a subset of the male COS cases.

Source: American Journal of Medical Genetics Part B: Neuropsychiatric Genetics - October 30, 2018 Category: Genetics & Stem Cells Authors: Amirthagowri Ambalavanan, Boris Chaumette, Sirui Zhou, Pingxing Xie, Qin He, Dan Spiegelman, Alexandre Dionne ‐Laporte, Cynthia V. Bourassa, Martine Therrien, Daniel Rochefort, Lan Xiong, Patrick A. Dion, Ridha Joober, Judith L. Rapoport, Tags: RESEARCH ARTICLE Source Type: research