Differences in First Trimester Maternal Metabolomic Profiles in Pregnancies Conceived from Fertility Treatments.

Conclusions: Metabolomic profiles differ between spontaneous and infertility pregnancies, likely driven by IVF. Elevated steroids and their metabolites are likely due to increased hormone production from placenta reprogrammed from fertility treatments which may contribute to adverse outcomes associated with infertility and treatments utilized.
PMID: 30445606 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - November 15, 2018 Category: Endocrinology Authors: Sun T, Lee B, Kinchen J, Wang ET, Gonzalez TL, Chan JL, Rotter JI, Chen YI, Taylor K, Goodarzi MO, Rich SS, Farber CR, Williams J, Pisarska MD Tags: J Clin Endocrinol Metab Source Type: research