Scutellarin alleviates blood-retina-barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy.

In conclusion, SC alleviates BRB breakdown via abrogating retinal inflammatory responses and subsequent oxidative stress injury initiated by microglia cells that is activated by hyperglycemia during DR development. PMID: 30447218 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30447218?dopt=Abstract

Source: Biochemical Pharmacology - November 14, 2018 Category: Drugs & Pharmacology Authors: Mei X, Zhang T, Ouyang H, Lu B, Wang Z, Ji L Tags: Biochem Pharmacol Source Type: research