pouC regulates expression of bmp4 during atrioventricular canal formation in zebrafish

ConclusionsTaken together, our study establishespouC as a novel transcriptional input into the regulatory hierarchy that drives AVC morphogenesis in zebrafish. We anticipate that these findings will inform future efforts to explore functional conservation in mammals and potential association with atrioventricular septal defects (AVSDs) in humans.This article is protected by copyright. All rights reserved.

Source: Developmental Dynamics - November 16, 2018 Category: Molecular Biology Authors: Minoti Bhakta, Mahesh S. Padanad, John P. Harris, Christina Lubczyk, James F. Amatruda, Nikhil V. Munshi Tags: Research Article Source Type: research