Intrathecal central nervous system prophylaxis in patients with diffuse large B-cell lymphoma at an academic healthcare system

This single-center study of 112 DLBCL patients evaluated indices predicting CNS relapse and outcomes related to the use of intrathecal prophylaxis of which the benefit is not well described. No difference was found in the rate of CNS relapse regardless of baseline risk or administration of intrathecal prophylaxis due to a low relapse rate and physician practices varied widely.
Source: Clinical Lymphoma, Myeloma and Leukemia - Category: Hematology Authors: Source Type: research