Genetic determinants of steatosis and fibrosis progression in pediatric non ‐alcoholic fatty liver disease

ConclusionsThis study provides evidence for the role of PNPLA3 as a determinant of portal NAFLD localization and severity of portal fibrosis in children and adolescents, the risk variant being associated with an impaired hepatic retinol metabolism.This article is protected by copyright. All rights reserved.

Source: Liver International - November 16, 2018 Category: Gastroenterology Authors: Christian A. Hudert, Silvia Selinski, Birgit Rudolph, Hendrik Bl äker, Christoph Loddenkemper, Ria Thielhorn, Nikolaus Berndt, Klaus Golka, Cristina Cadenas, Jörg Reinders, Stephan Henning, Philip Bufler, Peter L. M. Jansen, Hermann‐Georg Tags: Original Article Source Type: research