Weekly Postings

See something of interest? Please share our postings with colleagues in your institutions! Spotlight Deadline Extended! Apply by November 23 to participate in the 2019 Critical Appraisal Institute for Librarians! – Craving more confidence in leading EBM sessions for medical students? Puzzled on how to guide students about study design and in depth critical appraisal? Frustrated with statistics? This six week online program will develop librarian’s critical appraisal skills via enhanced understanding of research design, biomedical statistics, and clinical reasoning to apply knowledge in teaching target populations. The program will take place January 23-March 4, 2019. Participants may be eligible for up to 35 MLA CE credits (approval pending). Applications Due: Applications for the NNLM All of Us Community Engagement Award (up to $19,000) are due today, November 16. National Network of Libraries of Medicine News Due to the University of Pittsburgh holiday closure, MAR offices will be closed next week on November 22 and 23. On November 13, NNLM MAR staff partnered with Lydia Collins from the Training and Education Center (TEC) to participate in a National Institute on Drug Abuse (NIDA) Twitter chat, focusing on how to host a successful event for National Drug and Alcohol Facts Week (NDAFW). NDAFW is coming up in January 2019, so it’s the perfect time to start thinking about how your library or institution can get involved. If you are considering an event ...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news

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Date: Wednesday, 07 17, 2019; Speaker: Mary Kearney, PhD, Head, Translational Research Unite, HIV Dynamics and Replication Program, Center, National Cancer Institute; https://bit.ly/2RyT8Kw
Source: NIH Calendar of Events - Category: American Health Source Type: events
ConclusionThus our results showed that higher IL-37 was associated with increased insulin sensitive in elderly type 2 DM patients through suppressing the gut microbiota dysbiosis.
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
Hospitals and insurance companies will fight the order, which could reveal their secret negotiations.
Source: NYT - Category: American Health Tags: Health Insurance and Managed Care Prices (Fares, Fees and Rates) Executive Orders and Memorandums Health and Human Services Department Trump, Donald J Azar, Alex M II Source Type: news
In this study, we constructed a dual function nanosystem, copper sulfide nanoplatform loaded with the chemotherapeutic drug docetaxel wrapped by a conjugated polymer-peptide for targeted chemo-phototherapy. The nanoconstruct has been successfully designed with a size of 186.1 ± 5.2 nm, a polydispersity index of 0.18 ± 0.01, and zeta potential of −16.4 ± 0.1 mV. The enhanced uptake and near-infrared-responsive behavior of the nanosystem resulted in efficient drug release, photothermal ablation, effective cytotoxic activity, and potentiated reactive oxygen sp...
Source: Nanomedicine: Nanotechnology, Biology and Medicine - Category: Nanotechnology Source Type: research
It could depend on how much the health care system resembles the Danish concrete market.
Source: NYT - Category: American Health Authors: Tags: Prices (Fares, Fees and Rates) Health Insurance and Managed Care United States Economy Hospitals Concrete Source Type: news
Publication date: Available online 22 June 2019Source: Neuroscience LettersAuthor(s): Q. Leyrolle, S. Laye, A. NadjarAbstractMicroglia are key players in brain function by maintaining brain homeostasis across lifetime. They participate to brain development and maturation through their ability to release neurotrophic factors, to remove immature synapses or unnecessary neural progenitors. They modulate neuronal activity in healthy adult brains and they also orchestrate the neuroinflammatory response in various pathophysiological contexts such as aging and neurodegenerative diseases. One of the main features of microglia is t...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
In this study, we used operant self-administration and yohimbine-induced reinstatement models to examine relapse-like behavior in P rats. Our previous work has demonstrated that P rats show increased expression of the neurokinin-1 receptor (NK1R) in the central nucleus of the amygdala (CeA), and this functionally contributes to escalated alcohol consumption in this strain. We hypothesized that P rats would show increased sensitivity to yohimbine-induced reinstatement that is also mediated by NK1R in the CeA. Using Fos staining, site-specific infusion of NK1R antagonist, and viral vector overexpression, we examined the infl...
Source: Neuroscience - Category: Neuroscience Source Type: research
Insurance companies say they are owed some $12 billion promised to them in “risk corridor” provisions of the Affordable Care Act.
Source: NYT - Category: American Health Authors: Tags: Health Insurance and Managed Care Patient Protection and Affordable Care Act (2010) Supreme Court (US) Obama, Barack United States Politics and Government Source Type: news
The Food and Drug Administration (FDA) on Fridayapproved Vyleesi (bremelanotide) to treat premenopausal women for acquired, generalized hypoactive sexual desire disorder (HSDD). HSDD (classified as female sexual interest/arousal disorder inDSM-5) is characterized by low sexual desire that causes distress and cannot be explained by a comorbid physical or psychiatric illness, the side effects of substance use or medications, or severe relationship problems. Acquired HSDD means a woman has previously experienced sexual desire (it has not been a lifelong problem).“There are women who, for no known reason, have reduced se...
Source: Psychiatr News - Category: Psychiatry Tags: blood pressure female sexual interest/arousal disorder hypoactive sexual desire disorder naltrexone premenopausal women sexual dysfunction Vyleesi Source Type: research
ConclusionsThe degree of aspirin effect immediately prior to cardiac surgery was weakly associated with the risks of postoperative bleeding and allogeneic blood product transfusion, suggesting that measuring aspirin-induced antiplatelet effect prior to cardiac surgery may be useful as an adjunct in optimizing patient blood management for patients who are at high-risk of bleeding and requiring allogeneic blood transfusion.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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