TROP-2 exhibits tumor suppressive functions in cervical cancer by dual inhibition of IGF-1R and ALK signaling.

CONCLUSIONS: Collectively, our results support that TROP-2 exhibits tumor suppressor functions in cervical cancer through inhibiting the activity of IGF-1R and ALK.
PMID: 30429055 [PubMed - as supplied by publisher]

Source: Gynecologic Oncology - November 12, 2018 Category: Cancer & Oncology Authors: Sin STK, Li Y, Liu M, Ma S, Guan XY Tags: Gynecol Oncol Source Type: research