Orthognathic surgery induces genomewide changes longitudinally in DNA methylation in saliva

ConclusionPathway enrichment analysis of genes with suggestive significance demonstrated that altered DNA methylation in saliva of patients undergoing orthognathic surgery, possibly as a response to surgical stress or bone injury. Further studies with a large sample size and long ‐term observation are needed to validate the phenomena identified in this study.

https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.12998?af=R

Source: Oral Diseases - November 15, 2018 Category: ENT & OMF Authors: Tetsutaro Yamaguchi, Kazuyoshi Hosomichi, Masahiro Takahashi, Shugo Haga, Takatoshi Nakawaki, Yu Hikita, Koutaro Maki, Atsushi Tajima Tags: ORIGINAL ARTICLE Source Type: research