"TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure".

Conclusions TRPV1 is a physical and regulated component of the natriuretic peptide signaling system, and TRPV1 inhibition may provide a new treatment strategy for treating the loss of function associated with cardiac hypertrophy and remodeling. PMID: 30424709 [PubMed - as supplied by publisher]
Source: Channels - Category: Molecular Biology Tags: Channels (Austin) Source Type: research