Short ‐Chain Fatty Acids and Gut Microbiota in Multiple Sclerosis

ConclusionsStudies of EAE in mice suggest that SCFAs may play a role in the development and progression of EAE, but so far this has not been confirmed in humans. An aberrant gut microbiota in MS patients has been reported to be differentially abundant compared with healthy controls, although with little consistency in the bacterial taxa. Further investigations are required to elucidate the involvement of the gut microbiota and its metabolites, including potential beneficial effects of SCFAs, in the development and course of MS.This article is protected by copyright. All rights reserved.

Source: Acta Neurologica Scandinavica - November 14, 2018 Category: Neurology Authors: P Melbye, A Olsson, T H Hansen, H. B S øndergaard, A. B Oturai Tags: Review Article Source Type: research