Effects of glial glutamate transporter activator in formalin ‐induced pain behavior in mice

ConclusionThese results suggest that the GLT ‐1 activator LDN‐212320 prevents nociceptive pain by upregulating astroglial GLT‐1 expression in the hippocampus and ACC. Therefore, GLT‐1 activator could be a novel drug candidate for nociceptive pain.This article is protected by copyright. All rights reserved.

Source: European Journal of Pain - November 14, 2018 Category: Anesthesiology Authors: Ghallab Alotaibi, Shafiqur Rahman Tags: Original Article Source Type: research