Comparative study on the donor site aesthetic outcome between epidermal graft and split ‐thickness skin graft
Donor site aesthetic outcomes of epidermal graft (EG) vs split ‐thickness skin graft (SSG) have yet to be objectively compared. Here, we evaluate donor site healing using a validated scar assessment tool and digital colorimetric technique, which compares colour in a consistent and objective manner. Ten patients (SSG (n = 5) and EG (n = 5)) were included. Donor site scarring was evaluated using the Vancouver Scar Scale (VSS) at Week 6 and Month 3. Colorimetric measurement was performed at Weeks 3 and 6 and Month 3. The mean donor site healing time for EG was significantly shorter (EG: 4.6 days (95% c.i. 3.8‐5.3), SSG: 16.8 days (95% c.i. 13.3‐20. 1) (P = 0.003)). The VSS scores of the EG donor site were lower at Week 6 and Month 3(P
ConclusionsDespite the use of O-Z flap is quite unusual for back reconstruction, we believe that this flap represents a valid and safe alternative in selected cases, particularly in the elderly and medically compromised patients with multiple comorbidities.
Argentum Medicalâs antimicrobial dressings received an extra bit of validation after strong results from recent lab findings. The Geneva, IL-based companyâs Silverlon antimicrobial dressing was found to effectively kill Candida Auris (C. Auris), the emerging âsuperbugâ causing invasive, potentially fatal human infection in more than 30 countries, including the U.S. Argentum Medical commissioned Microbiological Consultants, an independent FDA-registered pharmaceutical testing laboratory, to establish if its metallic wound dressings can destroy C. Auris ...
We report an unusual case of a 53-year-old male with fistula, ectropion and lagophthalmos due to lateral frontal rhinosinusitis. Two years ago, he presented soft erythematous swelling at internal epicanthus. A year and a half before, he presented upper eyelid fistula secretion drainage, cicatricial ectropion and lagophthalmos. No otorhinolaryngological or visual discomfort was reported. Ophthalmology performed ectropion surgical repair using skin grafting, with no improvement. They requested magnetic resonance imaging which showed a suggestive image of frontal lateral sinusitis, being transferred to the Otorhinolaryngology...
Journal of Wound Care,Volume 28, Issue 9, Page 624-628, September 2019.
This study reports the clinical results of large skin grafts after sarcoma resection or traumatic injury repair.Wounds
CONCLUSIONS: In this small series, we found fewer complications than have been observed in prior studies, despite our series consisting solely of higher-risk, older patients. We believe this may have been attributable to the period of delay before placing the flap, which has been previously associated with higher flap survival and which allows for an extra recipient-site débridement. We believe this procedure can be performed by appropriately trained orthopaedic surgeons because it does not need microsurgery. LEVEL OF EVIDENCE: Level IV, therapeutic study. PMID: 31513016 [PubMed - as supplied by publisher]
Since the 1980s, deep and extensive skin wounds and burns are treated with autologous Split-Thickness Skin Grafts, or Cultured Epidermal Autografts (CEAs) when donor sites are limited. However, the clinical use of CEAs often remains unsatisfactory due to poor engraftment rates, altered wound healing and reduced skin functionality.In the past few decades, Mesenchymal Stromal Cells (MSCs) have raised much attention due to their anti-inflammatory, pro-trophic and pro-remodeling capacities. More specifically, gingival MSCs have been shown to possess enhanced wound healing properties compared to other tissue sources.
CONCLUSIONS This study confirms that upside-down grafting of subconfluent monolayers of serum-free cultured human keratinocytes on esterified hyaluronic acid membranes is a suitable means to transfer actively proliferative keratinocytes, and reduces wound contraction. Compared to standard grafting protocols of cultured epithelium, such as CEA sheet grafts, it is easier to apply, does not need enzymatic detachment of cells from the culture dish, and limits the number of production steps required. PMID: 31490908 [PubMed - in process]
In the free radial forearm flap (FRFF) and free fibula osteofasciocutaneous flap (FFOF) cases, skin grafts are often required for the donor site defects. Several methods for repairing such defects have been reported,1 most of which were achieved using split-thickness skin graft and full-thickness skin graft (FTSG). However, regardless of the skin graft type harvested from the distant sites, these may lead to further complications and aesthetic damages. Local FTSG methods involving harvesting from the ipsilateral forearm or lower leg to avoid a second donor site have been reported.
Conclusions Early, additional preoperative administration of cefazolin was able to significantly increase peak tissue concentrations during surgery compared with the standard protocol. No difference, however, could be achieved in the percentage of time during which the concentration exceeded the MIC. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents | Abstract | Full text