Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome.

Conclusions: P2X7R could trigger the activation of NLRP3 inflammasome, and the activated P2X7R/NLRP3 inflammasome in podocytes might be involved in the podocyte damage of ORG. PMID: 30425198 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30425198?dopt=Abstract

Source: Chinese Medical Journal - November 15, 2018 Category: General Medicine Authors: Hou XX, Dong HR, Sun LJ, Yang M, Cheng H, Chen YP Tags: Chin Med J (Engl) Source Type: research