EGFR mono-antibody salvage therapy for locally advanced and distant metastatic penile cancer: Clinical outcomes and genetic analysis

For locally advanced (including inguinal and pelvic lymph node metastatic disease) and distant metastatic penile squamous cell carcinoma (PSCC), multimodal treatments utilizing surgery, chemoradiotherapy and/or chemotherapy continue to be the most popular treatment regimen. Although several chemotherapy regimens combined with surgery have achieved encouraging short-term efficacies, long-term survival for those patients remains poor [1,2]. For patients with chemotherapy-failed experience, therapeutic options are even more limited.

Source: Urologic Oncology: Seminars and Original Investigations - November 14, 2018 Category: Urology & Nephrology Authors: Kang-bo Huang, Ran-yi Liu, Qi-hua Peng, Zai-shang Li, Li-juan Jiang, Sheng-jie Guo, Qiang-hua Zhou, Ting-yu Liu, Chuang-zhong Deng, Kai Yao, Zi-ke Qin, Zhuo-wei Liu, Yong-hong Li, Hui Han, Fang-jian Zhou Tags: Original article Source Type: research