Linking a cell-division gene and a suicide gene to define and improve cell therapy safety

Linking a cell-division gene and a suicide gene to define and improve cell therapy safetyLinking a cell-division gene and a suicide gene to define and improve cell therapy safety, Published online: 14 November 2018; doi:10.1038/s41586-018-0733-7Introduction of a suicide gene together with a linked cell-division gene to generate a safe-cell system enables the selective elimination of proliferating cells after cell transplantation in mouse models of cell therapy.

Source: Nature AOP - November 14, 2018 Category: Research Authors: Qin Liang Claudio Monetti Maria V. Shutova Eric J. Neely Sabiha Hacibekiroglu Huijuan Yang Christopher Kim Puzheng Zhang Chengjin Li Kristina Nagy Maria Mileikovsky Istvan Gyongy Hoon-Ki Sung Andras Nagy Source Type: research