FAST Phase III RCT of Radiotherapy Hypofractionation for Treatment of Early Breast Cancer: 10-Year Results (CRUKE/04/015)

The UK FAST trial tested 5 fractions (Fr) of 5.7 Gy and 6.0 Gy against 25 Fr of 2.0 Gy in women prescribed whole breast radiotherapy (no boost) after local excision of early breast cancer. Analysis of primary endpoint (normal tissue effects [by photograph]) showed that the 28.5 Gy/5 Fr regimen appeared similar to control. Further follow-up now enables analysis of 10-year outcomes.

Source: International Journal of Radiation Oncology * Biology * Physics - November 15, 2018 Category: Radiology Authors: A.M. Brunt, J. Haviland, M. Sydenham, H. Algurafi, A. Alhasso, P. Bliss, D. Bloomfield, M. Emson, A. Goodman, A. Harnett, H. Passant, Y.M. Tsang, D. Wheatley, J. Bliss, J. Yarnold Source Type: research