Risk Factors ID'd for Persistent Atopic Dermatitis in Kids

(MedPage Today) -- Could help clinicians personalize disease prediction
Source: MedPage Today Pediatrics - Category: Pediatrics Source Type: news

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Atopic dermatitis is a highly prevalent, chronic, relapsing disease in both adults and children. On the severity spectrum, lower-end patients benefit from small amounts of topical anti-inflammatory treatments ...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
ConclusionsThis report suggests that systemic immunotherapy with or without topical interferon is effective in treatment of malignant melanoma of the conjunctiva. Therefore, it can be considered for patients with advanced local conjunctival melanoma, those who refuse orbital exenteration surgery and those with systemic metastasis.
Source: Journal for Immunotherapy of Cancer - Category: Cancer & Oncology Source Type: research
The aim of this Letter to the Editor was to report some methodological shortcomings in the recently published article “Application of red light phototherapy in the treatment of radioactive dermatitis in patien...
Source: World Journal of Surgical Oncology - Category: Cancer & Oncology Authors: Tags: Correspondence Source Type: research
ConclusionsThe high incidence of MRSA acquisition found among AD patients and the risk factors associated show that an effective surveillance of MRSA colonization in these patients is needed.
Source: Journal of Microbiology, Immunology and Infection - Category: Microbiology Source Type: research
ConclusionThis case highlights the importance of using caution when combining radiation with the new targeted therapies. Until more data becomes available, physicians are recommended to exercise clinical judgment when deciding on whether to continue or discontinue a CDK4/6 inhibitor in a patient who may need radiation.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
The mechanisms leading to allergic skin inflammation such as atopic dermatitis or urticaria are poorly defined. Here, we used a mouse model for IgE-dependent chronic allergic inflammation (IgE-CAI) to study the role of basophils and eosinophils for induction of pathology. Fc εRI expression in basophils was required for the ear swelling response and basophils promoted the expression of eosinophil recruiting chemokines in the ear. The ear swelling response could be prevented by prior infection of mice with helminths in an IgE-dependent manner.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
AbstractAllergic eosinophilic esophagitis (EoE) is a chronic, allergen-mediated inflammatory disease of the esophagus, and the most common cause of prolonged dysphagia in children and young adults in the developed world. While initially undistinguished from gastroesophageal reflux disease-associated esophageal eosinophilia, EoE is now recognized as a clinically distinct entity that shares fundamental inflammatory features of other allergic conditions and is similarly increasing in incidence and prevalence. The clinical and epidemiologic associations between EoE and other allergic manifestations are well established. In add...
Source: Clinical Reviews in Allergy and Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 21 March 2019Source: Journal of Food and Drug AnalysisAuthor(s): Hung-Yu Ko, Yi-Hui Lin, Chi-Jen Shih, Yen-Ling ChenAbstractPhenylenediamines (PDs), which are reported to cause allergic dermatitis and possess genotoxicity and carcinogenicity, are the ingredients used in permanent hair dyes. The fluorescent derivatization strategy coupled with micellar electrokinetic chromatography (MEKC) were established to analyze four PDs, including o-phenylenediamine (OPD), m-phenylenediamine (MPD), p-phenylenediamine (PPD) and toluene-2,5-diamine (PTD). Additionally, 5-(4, 6-dichlorotriazinyl) aminofl...
Source: Journal of Food and Drug Analysis - Category: Food Science Source Type: research
Publication date: Available online 20 March 2019Source: The Veterinary JournalAuthor(s): D.A. Yang, R.A. Laven, R.N. ChestertonAbstractTo investigate the effect of climate and farm management practices on prevalence of bovine digital dermatitis (BDD) in spring-calving farms in Taranaki, New Zealand, whole herd assessments of BDD were made on 57 farms which had been previously identified as having cows with BDD. Assessments of BDD lesions were made on five occasions between early lactation (September 2015) and drying-off (May 2016; at approximately 6-week intervals). Along with the clinical assessment, data on farm manageme...
Source: The Veterinary Journal - Category: Veterinary Research Source Type: research
PMID: 30888106 [PubMed - in process]
Source: Veterinary Dermatology - Category: Veterinary Research Authors: Tags: Vet Dermatol Source Type: research
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