Prevalence of FVIII inhibitors in severe haemophilia A patients: Effect of treatment and genetic factors in an Indian population

ConclusionThe overall prevalence of inhibitors in patients with severe haemophilia A is similar to that reported among patients receiving regular replacement therapy. The data from this study, limited by its retrospective and cross ‐sectional study design, would suggest that genetic rather than environmental are more likely to impact the development of inhibitors.

Source: Haemophilia - November 14, 2018 Category: Hematology Authors: Sachin David, Sukesh C. Nair, G. Surender Singh, Ansu Abu Alex, Saravanan Ganesan, Hamenth Kumar Palani, Nithya Balasundaram, Kavitha M. Lakshmi, Aditi Joshi, S. Kannan, Anu Korula, Fouzia Nambiatheyil Aboobacker, Aby Abraham, Biju George, S Tags: ORIGINAL ARTICLE Source Type: research