Cutaneous botryomycosis of the foot: A case report and review of literature
Kevin John, Karthik Gunasekaran, Thomas Alex Kodiatte, Ramya IyyaduraiIndian Journal of Medical Microbiology 2018 36(3):447-449Botryomycosis is a chronic bacterial infection that manifests clinically as tumours or plaques that are often ulcerated and have discharging sinuses draining small white-coloured granules. Therefore, they closely mimic mycetoma or other fungal infections. It is most commonly caused by Staphylococcus aureus. It can present as cutaneous or visceral disease. The cutaneous form can invade deep tissue leading to extensive destruction and disfigurement. A 31-year-old female presented with progressive swelling of her right foot over a period of 8 years. She had a disfigured right foot with multiple sinuses discharging pus. X-ray and magnetic resonance imaging of the foot showed invasion and destruction of the deep layers of the foot including the bone. Deep biopsy from the foot showed an abscess cavity with Gram-positive cocci within and bacterial culture grew S. aureus establishing the diagnosis of botryomycosis. Botryomycosis is a rare presentation of a common pathogen and needs to be considered while evaluating a chronic invasive subcutaneous infection.
In this study, we discovered potent p53-MDM2 inhibition by 2-thiobenzyl-3-formyl quinoline, 2-thio-1,2-dihydroquinoline-3-formyl N-substituted thiosemi-carbazone and fluorine substituted new pyridine and pyran derivatives by structure-based design.Graphical abstract
Publication date: Available online 19 October 2019Source: Sensors and Actuators B: ChemicalAuthor(s): Mahmoud Amouzadeh Tabrizi, Josep Ferré-Borrull, Lluis F. MarsalAbstractFoodborne Salmonella disease is a major public health concern. Therefore, it is crucial to design a reliable biosensor to the diagnosis of this disease. Herein, we fabricated an interferometric reflectance spectroscopy (IRS) based DNA sensor for the determination of Salmonella-specific DNA fragment concentration. For this purpose, the nanoporous anodic alumina (NAA) was first fabricated. The pore walls of NAA were then functionalized with 3-amino...
Publication date: Available online 19 October 2019Source: Inorganica Chimica ActaAuthor(s): Ayman K. El-Sawaf, El Hassane AnouarAbstractThe (E)-N'-(2-hydroxybenzylidene)morpholine-4-carbothiohydrazide (H2L) ligand and its chelates with Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) have been synthesized. Analytical and spectral data prove that the ligand acts a monobasic tridentate ligand coordinated via deprotonated phenolic O, azomethine N and thione S atoms (ONS chromophore) with cobalt(II), nickel(II) and copper(II) salts leading to two fused five and six-membered chelate rings. While with zinc(II) and cadmium(II) salts the...
CONCLUSIONRegardless of the high awareness of health problems related to alcohol and tobacco use, the usage was high among the rural population. So more effective behavioural change communication strategies should be designed and implemented in the area to improve the practice among the rural population.
ConclusionsThe present study suggests that GM abnormalities in the LPAs, which can be detected during the early stage of illness, may underlie impaired verbal communication and positive symptoms in patients with schizophrenia spectrum psychosis.
ConclusionsqMRI enables specific assessment of inflammation in synovium, cartilage, bone, tendons and entheses, and can facilitate a more consistent, personalized approach to diagnosis, characterisation and monitoring of disease.
DiscussionA previous failed arthroscopic Bankart repair was a significant independent risk factor for inferior outcome. Preoperative bony pathology did not explain the worse outcome from the revision vs. primary Latarjet procedure.Level of evidenceIV, cohort observational study.
CONCLUSION: Routine microbiological examination of patients with corneal ulcer is necessary in order to analyze and compare the changing trends of the etiology and their susceptibility patterns. PMID: 27994804 [PubMed]
Conclusions: Periodic review of infection-related data, as well as infection control practices, is essential to optimize clinical outcome in patients with pediatric malignancies.