Effect of metformin treatment in patients with type 2 diabetes with respect to glyoxalase 1 activity in atherosclerotic lesions.

CONCLUSIONS: Treatment with metformin in patients with type 2 diabetes is associated with enhanced GLO1-activity in atherosclerotic lesions. Regarding the macro- and microvascular complications in these patients further studies are needed to gain more insight into the effect of metformin on the GLO/MG system. PMID: 30421661 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30421661?dopt=Abstract

Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - November 13, 2018 Category: Surgery Authors: Peters AS, Wortmann M, Fleming TH, Nawroth PP, Bruckner T, Böckler D, Hakimi M Tags: Vasa Source Type: research