Obesity and Cancer Risk: Emerging biological mechanisms and perspectives
Continuously rising trends in obesity-related malignancies render this disease spectrum a public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as population attributable fraction, is 11.9% in men and 13.1% in women. There is convincing evidence that excess body weight is associated with an increased risk for cancer of at least 13 anatomic sites, including endometrial, esophageal, renal and pancreatic adenocarcinomas; hepatocellular carcinoma; gastric cardia cancer; meningioma; multiple myeloma; colorectal, postmenopausal breast, ovarian, gallbladder and thyroid cancers.
Source: Metabolism - Clinical and Experimental - Category: Biomedical Science Authors: Konstantinos I. Avgerinos, Nikolaos Spyrou, Christos S. Mantzoros, Maria Dalamaga Source Type: research
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