Fibrinogen measurement in liver disease: validation of the functional fibrinogen thromboelastography assay and a novel mathematical predictive model.

DISCUSSION: The results of the FF-TEG correlate well with those of routine fibrinogen assays in patients with liver cirrhosis. However, the FF-TEG assay does not discriminate between early and late stages of disease, pointing to a preserved fibrin clot strength in cirrhosis. Through linear regression models, fibrinogen levels can be accurately estimated using the Clauss method based on fibrinogen levels obtained in the cheaper PT-Fg.
PMID: 30418134 [PubMed - as supplied by publisher]

Source: Blood Transfusion - November 9, 2018 Category: Hematology Authors: Rizzo K, Vella K, Zammit D, Gatt P, Grima C, Inguanez MB, Gerada J, Ellul P, Vassallo M, Azzopardi N, Pocock J, Gatt A Tags: Blood Transfus Source Type: research