Use of prostaglandin E1 to treat pulmonary hypertension in congenital diaphragmatic hernia

Prostaglandin E1 (PGE) has been used to maintain ductus arteriosus patency and unload the suprasystemic right ventricle (RV) in neonates with congenital diaphragmatic hernia (CDH) and severe pulmonary hypertension (PH). Here we evaluate the PH response in neonates with CDH and severe PH treated with PGE.

Source: Journal of Pediatric Surgery - November 12, 2018 Category: Surgery Authors: Kendall M. Lawrence, Kelsey Berger, Lisa Herkert, Christine Franciscovich, Carol Lynn H. O'Dea, Lindsay N. Waqar, Emily Partridge, Brian D. Hanna, William H. Peranteau, Catherine M. Avitabile, Rachel K. Hopper, Natalie E. Rintoul, Holly L. Hedrick Source Type: research