Histopathological and molecular analysis of idiopathic pulmonary fibrosis lungs from patients treated with pirfenidone or nintedanib
ConclusionPirfenidone and nintedanib do not modulate expression of senescence markers, levels of p ‐SMAD3 or the amount of fibrosis in IPF lungs. Treated patients have less histopathological evidence of acute lung injury at the time of lung transplantation.
Source: Histopathology - Category: Pathology Authors: Yingwei Zhang,
Kirk D Jones,
Natalia Achtar ‐Zadeh,
Gary Green,
Jasleen Kukreja,
Biyun Xu,
Paul J Wolters Tags: Original Article Source Type: research