Systemic lupus erythematosus and lymphoma: Incidence, pathogenesis and biology

Systemic lupus erythematosus (SLE) is a multisystem auto-immune inflammatory disease, with prevalence ranging from 20-150 cases per 100,000 population [1]. It mostly affects women of childbearing age and can involve any vital organ, in particular brain, kidneys, skin, heart and blood. SLE shows diversity, ranging from mild to potentially fatal disease mostly due to end stage organ damage [1]. In addition to classical clinical manifestations, SLE may also present with associated co-morbidities, most significantly cardiovascular disease with accelerated atherosclerosis [2].
Source: Leukemia Research - Category: Hematology Authors: Source Type: research