Study suggests diabetes medication improves heart structure

(St. Michael's Hospital) The diabetes medication empagliflozin has important effects that can improve cardiac structure in people with Type 2 diabetes who also have heart disease, suggests a new study led by St. Michael's Hospital.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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AbstractAimsTo evaluate the risk of heart failure (HF) in patients with type 2 diabetes (T2D) complicated by development of intercurrent ischaemic heart disease (IHD), end ‐stage renal disease (ESRD), or both, compared to patients with T2D and no IHD and ESRD.Methods and resultsFrom Danish nationwide registries, we identified all patients with new ‐onset T2D with no history of HF between 1998 and 2015. Landmark analyses were used to estimate the 5‐year absolute risk of HF at several follow‐up times, and accounted for the occurrence of IHD and ESRD, identified before HF. The Aalen–Johansen estimator was used ...
Source: European Journal of Heart Failure - Category: Cardiology Authors: Tags: Research Article Source Type: research
Diabetes-induced tissue injuries in target organs such as the kidney, heart, eye, liver, skin, and nervous system contribute significantly to the morbidity and mortality of diabetes. However, whether the lung should be considered a diabetic target organ has been discussed for decades. Accumulating evidence shows that both pulmonary histological changes and functional abnormalities have been observed in diabetic patients, suggesting that the lung is a diabetic target organ. Mechanisms underlying diabetic lung are unclear, however, oxidative stress, systemic inflammation, and premature aging convincingly contribute to them. ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
CONCLUSION: Future research must highlight the importance of raising dementia awareness among, and providing information about dementia caregiving to, Bangladeshi community members, as well as providing religiously sensitive healthcare services. PMID: 32213774 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
This study, for the first time, shows that transplantation of non-autologous mitochondria from healthy skeletal muscle cells into normal cardiomyocytes leads to short-term improvement of bioenergetics indicating "supercharged" state. However, over time these improved effects disappear, which suggests transplantation of mitochondria may have a potential application in settings where there is an acute stress. Outlining Some of the Science Behind Partial Reprogramming at Turn.bio https://www.fightaging.org/archives/2020/03/outlining-some-of-the-science-behind-partial-reprogramming-at-turn-bio/ Tur...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Ashley convinced her husband, Travis, to join her in following the Wheat Belly lifestyle that began with the Wheat Belly 10-Day Grain Detox. Ashley lost 70 pounds, while Travis experienced both weight loss and health/emotional benefits. Travis elaborates: “I feel like I have a new lease on life and I feel better than I have ever felt in my entire life (40 years old). “I started this WOE at 285 lbs on July 21, 2019, so it’s been 8 months and I’m down 65 lbs. It took me a couple months before I finally felt like I had completely detoxed and felt great everyday. It’s a bit overwhelming at first b...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open Gliadin gluten grain-free Inflammation Weight Loss wheat belly Source Type: blogs
RARITAN, N.J., March 20, 2020 – The Janssen Pharmaceutical Companies of Johnson &Johnson announced today that it will unveil late-breaking data from its leading cardiovascular and metabolism portfolio during the virtual American College of Cardiology’s 69th Annual Scientific Session together with the World Congress of Cardiology (ACC.20/WCC) on March 28-30, 2020. Notably, four late-breaking abstracts for XARELTO® (rivaroxaban) will be presented, including data from the Phase 3 VOYAGER PAD study in patients with symptomatic peripheral artery disease (PAD) after lower-extremity revascularization.Click to ...
Source: Johnson and Johnson - Category: Pharmaceuticals Source Type: news
AbstractPurposeTo investigate associations of total dietary choline intake and its major dietary form, phosphatidylcholine, with type 2 diabetes risk.MethodsWe included 2332 men aged 42 –60 years at baseline in 1984–1989 from the Kuopio Ischaemic Heart Disease Risk Factor Study in eastern Finland. Dietary intakes were assessed with 4-d food recording at baseline. Type 2 diabetes diagnosis was based on self-administered questionnaires, fasting and 2-h oral glucose tolerance tes t blood glucose measurements, or by record linkage to national health registries. Multivariable-adjusted Cox proportional hazards r...
Source: European Journal of Nutrition - Category: Nutrition Source Type: research
(Natural News) Many Americans get less than the recommended amount of sleep. Poor sleep has been linked to a variety of chronic diseases like heart disease, obesity and Type 2 diabetes. Now, recent research suggests that poor sleep can also deteriorate memory performance, especially in older adults. The National Sleep Foundation‘s inaugural Sleep Health Index...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
You may have already heard the term “insulin resistance,” as it has been widely discussed by doctors and the media. But did you know that you can reduce or reverse it in the vast majority of people? Insulin resistance, i.e., the inability of the body’s cells, especially liver, muscle, and brain, to respond to insulin and allow blood sugar to enter cells, drives numerous abnormal health conditions including type 2 diabetes, hypertension, coronary heart disease, fatty liver, Alzheimer’s dementia, and cancer. It is therefore a driving force behind so many modern and common chronic health conditions. Yo...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open can belly fat can insulin resistance be reversed lose weight reduce belly fat reverse inflammation visceral fat wheat belly Source Type: blogs
Biomarkers may contribute to our understanding of the pathophysiology of various diseases. Type 2 diabetes (T2D) and coronary heart disease (CHD) share many clinical and lifestyle risk factors and several biom...
Source: Cardiovascular Diabetology - Category: Cardiology Authors: Tags: Original investigation Source Type: research
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