BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma

ConclusionsCombination of flow cytometry with BrdU or ki67/DAPI staining could become a standard for the determination of MM cell proliferation. Furthermore, in the context of new effective myeloma treatment options, assessment of MM cell proliferation may be valuable, in clinical trials, to identify novel agents that could significantly affect the small proliferative compartment of MM cells. © 2018 International Clinical Cytometry Society

Source: Cytometry Part B: Clinical Cytometry - November 12, 2018 Category: Molecular Biology Authors: Guilhem Requirand, Nicolas Robert, St éphanie Boireau, Laure Vincent, Anja Seckinger, Salaheddine Bouhya, Patrice Ceballos, Guillaume Cartron, Dirk Hose, Bernard Klein, Jérôme Moreaux Tags: Original Article Source Type: research