What Causes Post-Inflammatory Hypopigmentation?
Discussion Hypopigmentation can be worrisome for many families because of cosmesis and the worry that “something is wrong.” The normal natural changes in skin-tone over the year due to different light exposure and wide variations within individuals is not something that many people are aware of. Post-inflammatory hypopigmentation is a common cause of hypopigmentation. Vitiligo is the most common cause of depigmentation. Vitiligo is an acquired, depigmenting disorder with typical lesions appearing as milky white macules with distinct margins that are not scaly. Hair (including eyebrows and eyelashes) can be depigmented if it occurs in a particular area. It occurs in about 0.5-1% of the population and is the most common cause of depigmentation. Melanocytes are absent from the affected skin area. All ages and genders are affected. Vitiligo usually is of the non-segmental form where lesions are bilateral and symmetrical across the body. The segmental form is unilateral, band or segmental in distribution. The lesions can occur in any part of the body and for some people they are increased because of skin trauma (clothing constrictions in certain areas, i.e. Koebner phenomenon) Vitiligo has been known for centuries and social discrimination because of the white lesions has been intense at different times and in different cultures. Vitiligo was often confused with leprosy for instance in the past, leading to social stigma based similarities between the white skin lesion...
Conclusions: Hispanic/Latino ethnicity and private insurance status are independent predictors of biologic utilization, suggesting that biologic mechanisms may influence the increased use of biologics in Latinos with psoriasis. PMID: 32643972 [PubMed - as supplied by publisher]
Conclusion: MKTP is a safe and effective method for treating refractory vitiligo and nevus depigmentosus in Thai patients. PMID: 32643482 [PubMed - as supplied by publisher]
Authors: Madu PN, Syder N, Elbuluk N Abstract Postinflammatory hypopigmentation is an acquired form of hypopigmentation that occurs secondary to an exogenous or endogenous insult to the skin. It can occur in all skin phototypes but is more visually apparent in skin of color. Due in part to greater attention given to its counterpart, postinflammatory hyperpigmentation, there is dearth of literature describing this entity and treatment options remain limited. This review provides a comprehensive update on the pathogenesis, diagnostic evaluation and treatment of postinflammatory hypopigmentation, with a focus on newly...
CONCLUSION: Our study emphasizes the importance of adequate microbiological testing and initiating appropriate treatment early in the management of endogenous endophthalmitis. PMID: 32644869 [PubMed - as supplied by publisher]
CONCLUSION: prompt diagnosis, through fundus examination and FA, and proper antiviral therapy were the mainstays to counteract the posterior uveitis. Nowadays, vaccination is a safe weapon to efficaciously reduce the ZVZ incidence among general population. PMID: 32644840 [PubMed - as supplied by publisher]
CONCLUSION: Definite diagnosis of unilateral choroidal effusion was done. A comprehensive workup is needed to exclude potential malignant process. PMID: 32644830 [PubMed - as supplied by publisher]
Authors: Concha-Del Rio LE, Uribe-Reina P, De-La-Torre A Abstract Allergy to steroids is an uncommon and harmful condition that leads to a decrease in treatment options and increase in morbidity due to the suboptimal disease control. It can manifest as an immediate response or a delay manifestation. Worsening of underlying condition and not treatment response can indicate corticosteroids hypersensitivity as well. Despite its low prevalence, all clinicians should be aware of this condition and know the treatment options. This narrative review attempts to update information about corticosteroid allergy and we present...
CONCLUSION: Majority had noninfectious etiologies. Uveitis associated with juvenile idiopathic arthritis was rare. PMID: 32643984 [PubMed - as supplied by publisher]
CONCLUSION: Ophthalmologists play an important role in a hospital-wide toxicity team and need to include IRAEs in their differential diagnosis. Given new drug development, ophthalmologists may be the first to identify IRAEs. PMID: 32643982 [PubMed - as supplied by publisher]
Falls are a serious health problem in older adults. A limited number of studies assessed their multifactorial nature in geriatric ward patients. The aim of this study is to explore health, functional and nutritional correlates of experiencing fall(s) in th...
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