Idiopathic Granulomatous Mastitis: A Retrospective Cohort study between 44 patients with different treatment modalities

ConclusionIGM is an uncommon benign disease which is hardly distinguished from malignancy. There is not a significant difference among treatment modalities in term of time-to-healing and recurrence of disease. The result shows that surgery is outperformed by the shortest healing time. However, the surgical treatment must be chosen with careful due to high rate of wound complications. Multimodality treatment is recommended as the proper treatments for IGM patient.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research

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The presentation of idiopathic granulomatous mastitis can mimic breast cancer. Therefore, awareness of the condition is important for surgeons. The current series is the largest in a US population.
Source: Surgery - Category: Surgery Authors: Source Type: research
Mammary duct ectasia is when a milk duct in the breast becomes blocked and clogged up with fluid. It is not a serious condition and does not increase a person's risk of breast cancer. However, it may cause pain, tenderness, and swelling, and it can sometimes lead to an infection called mastitis. Learn more here.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Women's Health / Gynecology Source Type: news
ConclusionMammographic and ultrasound findings can highly suggest a diagnosis of granulomatous mastitis in an appropriate clinical context.
Source: Journal of Ultrasound - Category: Radiology Source Type: research
Publication date: Available online 7 May 2019Source: The SurgeonAuthor(s): S.P. Russell, C. Neary, S. Abd Elwahab, J. Powell, N. O'Connell, L. Power, S. Tormey, B.A. Merrigan, A.J. LoweryAbstractIntroductionPrimary breast abscesses occur in
Source: The Surgeon - Category: Surgery Source Type: research
In this study, we found that the activities of alkaline phosphatase (ALP) and mineralized nodules in MC3T3-E1 cells were both significantly increased after treatment with AG (5, 10, and 20 μM). Meanwhile, the mRNA and protein levels of osteoblastic marker genes in MC3T3-E1 cells after AG treatment were markedly increased compared with a control group. In addition, the levels of BMP-2, p-Smad1/5/9, and Runx2 were significantly elevated in AG-treated MC3T3-E1 cells. Moreover, we found that the protein levels of Erk1/2, p-Erk1/2, p38, p-p38, and p-JNK were also significantly increased in AG-treated MC3T3-E1 cells compared ...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
We report a case of PAN affecting the right breast in a young woman. A retrospective review was performed by searching Medline, Embase, Web of Science, the Cochrane Library, and Scopus for cases of systemic vasculitis involving the breast written in English up to June 1st, 2018. A 27-year-old woman presented with a painful mass in the right breast was diagnosed as PAN by the biopsy. She was treated with prednisone and methotrexate for 6  months, at which time her condition had stabilized and inflammatory markers had normalized. A total of 66 cases were identified, with granulomatosis with polyangiitis (GPA), giant cel...
Source: Rheumatology International - Category: Rheumatology Source Type: research
Conclusion: US can demonstrate or exclude a true mass against the background of a nodular breast parenchyma. Radiologists must be aware of malignant US features to avoid delays in the diagnosis of pregnancy-associated breast cancer.Breast Care
Source: Breast Care - Category: Cancer & Oncology Source Type: research
ConclusionAlthough clinical and radiological findings of patients with GM may mimic those of breast carcinoma, our study showed that women of childbearing age, especially among Hispanic ethnicity with a recent history of pregnancy or high prolactin level and newly tender mass-like lesion, in addition to new focal asymmetry on mammogram and heterogeneous hypoechoic irregular-shaped mass on ultrasound exam, should raise concern for GM. Non-invasive approach and clinical follow-up were the preferred treatment method.
Source: Breast Cancer Research and Treatment - Category: Cancer & Oncology Source Type: research
Abstract There are rare benign diseases that can mimic malignant breast neoplasms in the clinical exam and in mammography. We evaluated the contribution of an accessible procedure to most clinicians, the fine-needle aspiration cytology, to identify a rare mimicker of malignant breast neoplasms. A type 2 diabetic 85-year-old female presented with a 6-month history of a left breast lump. The physical exam and mammography were compatible with breast cancer. Nevertheless, after fine-needle aspiration cytology, the diagnosis was plasma cellmastitis. Once this rare diagnosis was established, the tumor was extirpated, and the fin...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
This study aimed to investigate the utility of a volumetric apparent diffusion coefficient (ADC) histogram method for distinguishing non–puerperal mastitis (NPM) from breast cancer (BC) and to compare this method with a traditional 2-dimensional measurement method. Materials and Methods Pretreatment diffusion-weighted imaging data at 3.0 T were obtained for 80 patients (NPM, n = 27; BC, n = 53) and were retrospectively assessed. Two readers measured ADC values according to 2 distinct region-of-interest (ROI) protocols. The first protocol included the generation of ADC histograms for each lesion, and various parame...
Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Breast Imaging Source Type: research
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