Holmes’ tremor from a lesion of the red nucleus in association with cerebral toxoplasmosis

This report presents the case of a patient who developed a tremor of her right arm, with hemiparesis and ataxia as a result of systemic and cerebral toxoplasmosis in association with AIDS. MRI brain imaging showed a lesion in the contralateral red nucleus in the rostral midbrain, consistent with toxoplasmosis, and confirming the diagnosis of a Holmes’ tremor. The patient responded well, symptomatically, to botulinum toxin (Botox) injections. This case illustrates the importance of neuroimaging in diagnosis of tremor disorders.

Source: Basal Ganglia - October 17, 2014 Category: Neurology Source Type: research