Mitochondrial DNA haplogroups and age at onset of Machado ‐Joseph disease/Spinocerebellar ataxia type 3: a study in patients from multiple populations

ConclusionsThese findings suggest that JT, W and X haplogroups seem to modify age at onset in Machado ‐Joseph disease; replication studies should be performed in European populations, where the frequency of the candidate modifiers is similar.This article is protected by copyright. All rights reserved.

Source: European Journal of Neurology - November 10, 2018 Category: Neurology Authors: A. Ramos, M. Planchat, A R. Vieira Melo, M. Raposo, U. Shamim, V. Suroliya, A.K. Srivastava, M. Faruq, H. Morino, R. Ohsawa, H. Kawakami, L.B. Jardim, ML Saraiva ‐Pereira, J. Vasconcelos, C. Santos, M. Lima Tags: Original Article Source Type: research