Inhibition of mTORC2/RICTOR Impairs Melanoma Hepatic Metastasis.

In conclusion, these results provide first evidence for a critical role of mTORC2/RICTOR in melanoma liver metastasis via cancer cell/HSC interactions.
PMID: 30404068 [PubMed - as supplied by publisher]

Source: Neoplasia - November 4, 2018 Category: Cancer & Oncology Authors: Schmidt KM, Dietrich P, Hackl C, Guenzle J, Bronsert P, Wagner C, Fichtner-Feigl S, Schlitt HJ, Geissler EK, Hellerbrand C, Lang SA Tags: Neoplasia Source Type: research