Propofol-sparing effect of different concentrations of dexmedetomidine : Comparison of gender differences.

CONCLUSION: Gender significantly influenced the calculated effect-site EC50 of propofol for LOC after pretreatment with different concentrations of intravenous dexmedetomidine. It was concluded that an additive interaction could describe the results seen. Thus, gender has to be considered when these drugs are co-administered. PMID: 30406275 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30406275?dopt=Abstract

Source: Der Anaesthesist - November 7, 2018 Category: Anesthesiology Authors: Xiong M, Zheng Z-, Hu ZR, He J, Madubuko U, Grech D, Zhang XA, Xu B Tags: Anaesthesist Source Type: research

More News: Anesthesia | Anesthesiology | Diprivan | Propofol | Study