P166 - Non-invasive detection of bladder cancer and its recurrence in exfoliated cells from urine sediment by assessing the presence of telomerase activity
Publication date: November 2018Source: European Urology Supplements, Volume 17, Issue 14Author(s): N. Potoldykova, A.I. Glukhov, A.Z. Vinarov, S.A. Gordeev, D.V. Enikeev, P.V. Glybochko
In this study, we computed the relative abundances of 24 immune cells based on the expression profiles of MIBC patients using single ‐sample gene set enrichment analysis (ssGSEA). Unsupervised clustering analysis of the 24 immune cells was performed to classify MIBC patients into different immune‐infiltrating groups. Genome (gene mutation and copy number variation), transcriptome (mRNA, lncRNA, and miRNA), and functional enri chment were found to be heterogeneous among different immune‐infiltrating groups. We identified 282 differentially expressed genes (DEGs) associated with immune infiltration by comparing the exp...
This study paves the way for the future use of not only g ‐C3N4 but also other 2D nanomaterials in cancer therapy.
Publication date: Available online 27 February 2020Source: Chemico-Biological InteractionsAuthor(s): Mengzhao Zhang, Hongxia Du, Lu Wang, Yangyang Yue, Pu Zhang, Zhixin Huang, Wei Lv, Jianbin Ma, Qiuya Shao, Minghai Ma, Xiao Liang, Tao Yang, Weiyi Wang, Jin Zeng, Guanqiu Chen, Xinyang Wang, Jinhai Fan
Publication date: Available online 26 February 2020Source: European UrologyAuthor(s): Wei Liu, Xiaoping Liu, Sheng Li
Condition: Bladder Cancer Intervention: Diagnostic Test: Metadherin Sponsor: Assiut University Not yet recruiting
Conclusion: These updated French guidelines will contribute to increase the level of urological care for the diagnosis and treatment for NMIBC and MIBC. PMID: 32093463 [PubMed - in process]
Publication date: Available online 26 February 2020Source: Practical Radiation OncologyAuthor(s): Kimberly R. Gergelis, Cole R. Kreofsky, Christopher S. Choo, Jason Viehman, W Scott Harmsen, Scott C. Lester, Thomas M. Pisansky, Brian J. Davis, Bradley J. Stish, Richard Choo
Publication date: Available online 26 February 2020Source: Urology Case ReportsAuthor(s): Manabu Takai, Daiki Kato, Koji Iinuma, Yuka Muramatsu Maekawa, Keita Nakane, Tomohiro Tsuchiya, Shigeaki Yokoi, Takuya Koie
CONCLUSIONS: We discovered a vital regulatory mechanism of hsa_circ_0017247 in BLCA which might serve as a new therapeutic intervention for BLCA patients. PMID: 32096177 [PubMed - in process]
This study provides the first evidence of the urinary TERT promoter mutations to be used as simple and cost-effective non-invasive biomarkers for the early detection of bladder cancer.