P173 - Laparoscopic-assisted robotic retroperitoneal lymph node dissection (R-RPLND) for non seminomatous germ cell tumor of testis: Single centre initial experience

Publication date: November 2018Source: European Urology Supplements, Volume 17, Issue 14Author(s): Y. Thyavihally, S. Waigankar, A. Pednekar, S. Ramani
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research

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ConclusionThis is the first case of robot-assisted laparoscopic retroperitoneal lymph node dissection with concomitant inferior vena cava thrombectomy and reconstruction for metastatic mixed testicular germ cell cancer published to date. This complicated surgical procedure was facilitated by the innovative usage of three-dimensional image reconstruction for defining the vena cava tumor thrombus, a robotic ultrasound probe for intraoperatively defining the vena cava tumor thrombus, and vena cavoscopy using a flexible ureteroscope.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Testicular Germ Cell Tumor (GCT) is the most common solid tumor in men between the ages of 20-44. Men diagnosed with GCT have excellent survival rates due to advances in the multimodal treatment paradigm of chemotherapy, radiation therapy and surgery. When considering the adequate treatment, several variables should be investigated and known to select the proper procedure. Therefore, when considering Testicular Intra-Epithelial Neoplasia, organ-sparring treatment, such as radiotherapy or organ-sparring surgery should be considered, reaching a cure rate of 98%. However, when the case is of a seminoma or a non-seminoma, orch...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Rationale: Yolk sac tumors (YSTs) are malignant germ cell tumors that secrete alpha-fetoprotein (AFP). These tumors commonly develop in infants, young children, and young women and often originate in the gonads. Primary endometrial YST is a very rare malignancy, and a primary endometrial YST in the absence of abnormal AFP levels is even rarer. Patient concerns: A 38-year-old woman presented with the chief complaint of prolonged menstruation and increased menstrual bleeding with a duration of more than 2 months. Diagnoses: Postoperative pathology confirmed a diagnosis of endometrial YST with metastasis to the greate...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Complete Androgen Insensitivity Syndrome (CAIS), is an X-linked genetic disease, where female-appearing 46XY patients have testes located in the internal inguinal ring or in the labia majora. In the past, prophylactic gonadectomy has been performed, given risks of germ cell tumor development. However, gonadal surveillance algorithms have been proposed as an alternative, due to challenges with replacement therapy (HRT) and ethical concerns. In this case study, we review ultrasonographic changes in gonads of 3 patients with CAIS, and pathology results with one patient who elected for laparoscopic cystectomy as part of her surveillance.
Source: Journal of Pediatric and Adolescent Gynecology - Category: OBGYN Authors: Source Type: research
Complete Androgen Insensitivity (CAIS) is a Difference of Sex Development, where there is complete androgen receptor resistance, leading to a female phenotype, despite the presence of normal testes. There is a recognized risk of testicular germ cell tumor in adulthood as high as 15%, and gonadectomy is usually performed in late adolescence or early adulthood.
Source: Journal of Pediatric and Adolescent Gynecology - Category: OBGYN Authors: Source Type: research
Publication date: Available online 9 June 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): Dimitrios Nasioudis, Evelyn Minis, Eloise Chapman-Davis, Melissa K. Frey, Thomas A. Caputo, Steven S. Witkin, Kevin HolcombAbstractStudy ObjectiveEvaluate the prevalence, trends, and outcomes of minimally invasive surgical (MIS) staging of malignant ovarian germ cell tumors (MOGCTs) apparently confined to the ovary.DesignRetrospective cohort study (Canadian Task Force classification II-2).SettingParticipating hospitals in the National Cancer Data Base.PatientsWomen diagnosed between 2010 and 2014 with a MOGCT apparently...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Publication date: Available online 9 June 2018Source: Journal of Minimally Invasive GynecologyAuthor(s): Dimitrios Nasioudis, Evelyn Minis, Eloise Chapman-Davis, Melissa K. Frey, Thomas A. Caputo, Steven S. Witkin, Kevin HolcombABSTRACTStudy objectiveEvaluate the prevalence, trends and outcomes of minimally invasive surgical staging (MIS) of malignant ovarian germ cell tumors (MOGCTs) apparently confined to the ovary.DesignRetrospective cohort study (Canadian Task Force classification II-2)SettingParticipating hospitals in the National Cancer Data BasePatientsWomen diagnosed between 2010-2014 with a MOGCT apparently confin...
Source: Journal of Minimally Invasive Gynecology - Category: OBGYN Source Type: research
Discussion: Encouraged by favorable early oncologic and safety outcomes for treatment of clinical stage (CS) I nonseminomatous germ cell tumor (NSGCT), the R-RPLND affords the same recovery advantages as the laparoscopic retroperitoneal lymph node dissection (L-RPLND) while offering greater dexterity, superior visualization, and a theoretically shorter learning curve for the surgeon. While R-RPLND has a promising future in the management of patients with primary and postchemotherapy NSGCT, larger and more vigorous prospective studies are needed before supplanting the open RPLND as the gold standard approach for primary low...
Source: Advances in Urology - Category: Urology & Nephrology Tags: Adv Urol Source Type: research
We report a case of a 29-year-old woman with ACC synchronously followed by an ovarian malignant mixed germ cell tumor. We describe the clinical, histopathological, and immunohistochemical findings and review the English literatures. So far, as we know, the patient presented here is the first case with synchronous malignant tumors of the adrenal gland and ovary. Diagnoses: She was diagnosed with ovarian malignant mixed germ cell tumor with admixture of dysgerminoma and yolk sac tumor after ACC. Interventions: The left adrenal tumor was resected laparoscopically on April 28, 2017. A total laparoscopic hysterectomy with...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Retroperitoneal lymph node dissection (RPLND) is a well-established treatment for post chemotherapy residual mass in non-seminomatous germ cell tumor (NSGCT) as it has diagnostic as well as therapeutic advantage. Although the open RPLND is gold standard, but due to high postoperative morbidity and poor cosmesis due to long midline abdominal incision laparoscopic retroperitoneal lymph node dissection (L-RPLND), robot assisted laparoscopic retroperitoneal lymph node dissection(RA-RPLND) has been described.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Surgical Technology & Simulation: Instrumentation Technology I Source Type: research
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