Triclosan Suppresses Testicular Steroidogenesis via the miR-6321/JNK/ Nur77 Cascade

Conclusion: Taken together, the miR-6321/Map3k1-regulated JNK/c-Jun/ Nur77 cascade contributes to TCS-caused suppression of testicular steroidogenesis, and the decrease in 5 α-Reductase expressions may be the compensatory mechanism.Cell Physiol Biochem 2018;50:2029 –2045

https://www.karger.com/Article/FullText/495049

Source: Cellular Physiology and Biochemistry - November 9, 2018 Category: Cytology Source Type: research