Treatment with secukinumab in multi-comorbid patients with psoriatic arthritis.

We report two cases of patients with PsA, one of them with a 14-year-long medical history, and the other with lung involvement. Several different DMARDs with overall modest efficacy and lack of tolerability were used in both cases before switching the patients to secukinumab. Secukinumab allowed for a rapid improvement of the patients' symptoms without any safety concern. Our experience may be useful to the current knowledge on 'real world' use of secukinumab, which appears to effective and safe in challenging patients with comorbidities and poor tolerability to previous used biological agents. PMID: 30403897 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research