The Starting Five: Vitamins for Improved Health

You're reading The Starting Five: Vitamins for Improved Health, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. “By the proper intakes of vitamins and other nutrients…you can, I believe, extend your life and years of well-being by twenty-five or even thirty-five years,” said Nobel Prize winning scientist Linus Pauling. Modern research has confirmed Pauling’s belief as it has identified five vitamins that may improve overall health. Vitamin D Vitamin D provides many important health benefits. It helps to build strong bones, regulates the calcium and phosphate levels in the body, encourages cell growth, strengthens the immune system, protects against certain forms of cancer, and improves mental health. Recent studies have also found that a person’s health can be improved at the most critical times when Vitamin D is given in combination with the nutritional supplement glutamine - an amino acid that occurs naturally in the body. Glutamine benefits the body in several ways. First, it is an important building block of proteins, which are essential to a strong immune system. Second, glutamine improves intestinal health. Third, it helps the body’s healing during injury and illness. A 2017 study found that trauma patients receiving Vitamin D and glutamine had a 62% lower death rate. The best sources of Vitamin D are certain types of fatty-fleshe...
Source: PickTheBrain | Motivation and Self Improvement - Category: Consumer Health News Authors: Tags: featured health and fitness pickthebrain self improvement vitamins what vitamins should i take Source Type: blogs

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Publication date: Available online 22 February 2019Source: SteroidsAuthor(s): Hye Joung Choi, Bao Ting ZhuAbstract2-Methoxyestradiol is an endogenous nonpolar metabolite of 17β-estradiol with a strong antitubulin activity. Earlier we showed that 2-methoxyestradiol increases the level and activity of cyclin B1/CDK1, which subsequently induces mitotic prometaphase arrest. In the present study, we demonstrate that upregulation of cyclin B1/CDK1 is responsible for the increased phosphorylation of the anti-apoptotic proteins Bcl-2 and Bcl-XL in 2-methoxyestradiol-induced, mitotically-arrested cancer cells. Additional analy...
Source: Steroids - Category: Drugs & Pharmacology Source Type: research
This study suggests that the U11-DOX/CUR NPs have promising potential for combination treatment of lung cancer.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Jung Sun Park, Hoon In Choi, Dong-Hyun Kim, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan KimAbstractThe p-cresyl sulfate accumulates in kidney disease and may be involved in renal injury. α-Lipoic acid (α-LA) acts as an antioxidant in cell injury. We investigated the effects of α-LA treatment on p-cresyl sulfate-induced renal tubular injury. p-Cresyl sulfate induced cell death, and increased Bax/Bcl-2, cleaved caspase-3, Beclin-1, and LC3BII/LC3BI in human renal proximal tubular epithelial (HK-2) cells, whic...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
This study evaluated the pharmacological effect of the association of crude extract from the fruits of Pterodon pubescens (Pp) with the essential oil of Cordia verbenacea (Cv) in antinociception and anti-inflammatory experimental models. The effective doses of each extract and the combinations used in the associations of extracts were defined by acetic acid-induced writhing test. The separate extracts were also evaluated on formalin test. Interaction between extracts was assessed by isobologram method. The effects of different concentrations of associations (A50, A100 and A200) were evaluated on formalin test, tail flick a...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
In conclusion, we have verified that circVAPA is up-regulated in CRC patients’ tissues and plasma, and exerts oncogenic properties by sponging miR-101 in CRC. CircVAPA could serve as a promising biomarker and a therapeutic target for CRC.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Bing Wu, Heyuan Wang, Lenign Zhang, Chenglin Sun, Hang Li, Chunyan Jiang, Xiaodong LiuAbstractAs a key regulator of DNA translesion synthesis (TLS) pathway, RAD18 is reported to be abnormally expressed in many kinds of cancers. In glioma, RAD18 was overexpressed in the primary and recurrent glioblastoma multiforme specimens, and its overexpression weakened ionizing radiation-induced apoptosis in glioma A172 cells. Moreover, A172 cells with mutational P53 also showed enhanced radiation resistance. And RAD18 activation induced by cycli...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Lakshmi Priya Pasari, Amit Khurana, Pratibha Anchi, Mohd Aslam Saifi, Shivaraju Annaldas, Chandraiah GoduguAbstractAcute pancreatitis (AP) is an exocrine dysfunction of the pancreas where oxidative stress and inflammatory cytokines play a key role in induction and progression of the disease. Studies have demonstrated that antioxidant phytochemicals have been effective in improving pancreatitis condition, but there are no clinically approved drugs till date. Our study aims to assess the preventive activity of visnagin, a novel phytoch...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Lauren Tomlinson, Zhen Qi Lu, Robert A Bentley, Helen E. Colley, Craig Murdoch, Steven D. Webb, Michael J. Cross, Ian M. Copple, Parveen SharmaAbstractDose-dependent cardiotoxicity is the leading adverse reaction seen in cancer patients treated with doxorubicin. Currently, dexrazoxane is the only approved drug that can partially protect against this toxicity in patients, however, its administration is restricted to those patients receiving a high cumulative dose of anthracyclines. Investigations into the mechanisms of cardiotoxicity ...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
Publication date: April 2019Source: Biomedicine &Pharmacotherapy, Volume 112Author(s): Jaturon Kwanthongdee, Chotchanit Sunrat, Bamroong Munyoo, Patoomratana Tuchinda, Napason Chabang, Witchuda SaengsawangAbstractGlioblastoma is the most common and the most malignant form of brain tumor. This devastating tumor results in death within a year after diagnosis. Although the tumor mass can be surgically removed, glioma cells invade other areas in the brain leading to tumor recurrence and poor prognosis. Therefore, new agents that can overcome cancer cell invasion are urgently required. Phyllanthus taxodiifolius Beille (P. t...
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
ConclusionMS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased.Graphical abstract
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research
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