Discovery of a novel (R)-selective bacterial hydroxynitrile lyase from Acidobacterium capsulatum

In this study, database mining revealed a novel cupin HNL from Acidobacterium capsulatum ATCC 51196 (AcHNL), which was able to catalyse the (R)-selective synthesis of mandelonitrile with significantly better conversion (97%) and enantioselectivity (96.7%) than other cupin HNLs.
Source: Computational and Structural Biotechnology Journal - Category: Biotechnology Source Type: research