NIH grant supports research seeking heart disease treatment for kidney disease patients

(New York Institute of Technology) Researchers at New York Institute of Technology (NYIT) have secured a grant from the National Institutes of Health (NIH) that may allow for improved understanding of vascular calcification and prevent heart disease in chronic kidney disease patients.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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AbstractDiabetes mellitus affects over 20% of people aged  >  65 years. With the population of older people living with diabetes growing, the condition may be only one of a number of significant comorbidities that increases the complexity of their care, reduces functional status and inhibits their ability to self-care. Coexisting comorbidities may compete for the attention of the patient and their healthcare team, and therapies to manage comorbidities may adversely affect a person’s diabetes. The presence of renal or liver disease reduces the types of antihyperglycemic therapies available for us...
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
This article highlights the issues faced by older people with T2D, the risk factors for hypoglycemia in this population, and the challenges faced by health care providers regarding glycemic management in this patient group. PMID: 30724638 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - Category: Internal Medicine Tags: Postgrad Med Source Type: research
Publication date: February 2019Source: Molecular Genetics and Metabolism, Volume 126, Issue 2Author(s): Michael L. West, Mathieu C. Castonguay, Emily Chisholm, Kaye LeMoine
Source: Molecular Genetics and Metabolism - Category: Genetics & Stem Cells Source Type: research
ConclusionWith increasing pressure for cost containment in an era of bundled payment models, the very low rate of laboratory associated interventions suggest that routine postoperative laboratory tests is not justified. Obtaining laboratory after primary, unilateral TKA should be driven by patients’ risk factors.
Source: Journal of Clinical Orthopaedics and Trauma - Category: Orthopaedics Source Type: research
Cross-talk between the kidneys and the heart has long been appreciated. The kidneys are referred to in the Talmud —the central text of Judaism, written during approximately the 4th century AD—as the organs that “give the heart advice and counsel.”1 During the Middle Ages, the Italian physician Gentile da Foligno referred to heart disease as one of the major conditions that affected the color and output of urine.2 In the 19th century the English physician, Richard Bright, observed that cardiac hypertrophy was a common disorder in patients suffering from chronic kidney disease (CKD).
Source: Seminars in Nephrology - Category: Urology & Nephrology Authors: Source Type: research
ConclusionsDiabetes carries a significant health burden, and results vary across states. Efforts to prevent or delay diabetes or to improve diabetes management could reduce the health burden because of diabetes.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
THURSDAY, Dec. 6, 2018 -- Although fewer Americans are dying from heart disease and cancer, deaths from chronic kidney disease are on the rise, especially among young adults, a new study finds. " Unfortunately, chronic kidney disease is known as a...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Publication date: Available online 24 November 2018Source: Canadian Journal of CardiologyAuthor(s): Mark Hensey, Dale J. Murdoch, Janarthanan Sathananthan, David A. Wood, John G. WebbAbstractThe coexistence of chronic kidney disease (CKD) and severe aortic stenosis (AS) is common and the prevalence of both is rising. The two conditions are inherently linked in that significant CKD may accelerate the development of AS and severe AS may result in deteriorating kidney function. The volume of, and indications for transcatheter aortic valve implantation (TAVI) procedures are ever-increasing and there are many challenges that ne...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
ABSTRACTIn the general population and in heart disease, pulmonary hypertension (PH) is a strong and independent risk factor for mortality and adverse cardiovascular outcomes. We performed a systematic review and meta ‐analysis of longitudinal cohort studies of individuals with chronic kidney disease (CKD) of any‐stage (also including end‐stage kidney disease –ESKD‐ and kidney transplantation) stratified according to presence/absence of PH.18 eligible studies (10740 participants) were retrieved. PH had an overall pooled prevalence (PP) of 33% (95% CI 28 ‐42) and portended a higher risk of all‐cause mortali...
Source: Therapeutic Apheresis and Dialysis - Category: Hematology Authors: Tags: Review Source Type: research
Introduction:The presence of pulmonary hypertension (PH) in myeloproliferative disorders (MPD) has been evaluated in several small studies with mainly echocardiographic assessment of the right ventricular systolic pressures (RVSP). Left-sided heart disease is the most common cause of PH, and the incidence of diastolic dysfunction increases with age. Since MPD is more prevalent in older patients, it is unknown how much of PH is related to diastolic dysfunction. In addition, the presence and effect of concomitant cardiovascular diseases on overall mortality in these patients is unknown. To assess above knowledge gaps, we eva...
Source: Blood - Category: Hematology Authors: Tags: 634. Myeloproliferative Syndromes: Clinical: Poster III Source Type: research
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