Design of amidobenzimidazole STING receptor agonists with systemic activity

Design of amidobenzimidazole STING receptor agonists with systemic activityDesign of amidobenzimidazole STING receptor agonists with systemic activity, Published online: 07 November 2018; doi:10.1038/s41586-018-0705-yA small-molecule agonist for the cGAS–STING pathway has systemic activity in a mouse model of colon cancer.

https://www.nature.com/articles/s41586-018-0705-y

Source: Nature AOP - November 7, 2018 Category: Research Authors: Joshi M. Ramanjulu G. Scott Pesiridis Jingsong Yang Nestor Concha Robert Singhaus Shu-Yun Zhang Jean-Luc Tran Patrick Moore Stephanie Lehmann H. Christian Eberl Marcel Muelbaier Jessica L. Schneck Jim Clemens Michael Adam John Mehlmann Joseph Romano Angel Source Type: research