Identification of phase-II metabolites from human serum samples after oral intake of a willow bark extract

ConclusionThis is the first study to identify human metabolites of flavonoids, proanthocyanidins and salicylic alcohol derivatives of Salicis cortex beside salicylic acid or catechol. For the most characterized metabolites, anti-inflammatory activity has been described in the literature, and the present results are an important step in understanding the anti-inflammatory efficacy of willow bark in-vivo.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research