Development of clinical trials to extend healthy lifespan

We describe the rationale and collaborative, consensus building approach used to design the first aging outcome trial called Targeting Aging with Metformin. Through this case study, we outline features that could be more broadly extended to other geroscience-guided clinical trials, including a process for selecting biochemical and molecular markers of biologic age and we provide a perspective on the potential impact of clinical trials targeting aging.
Source: Cardiovascular Endocrinology - Category: Cardiology Tags: Review articles Source Type: research