Viruses, Vol. 10, Pages 615: Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System
Viruses, Vol. 10, Pages 615: Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System
Viruses doi: 10.3390/v10110615
Authors:
Danielle B. L. Oliveira
Giuliana S. Durigon
Érica A. Mendes
Jason T. Ladner
Robert Andreata-Santos
Danielle B. Araujo
Viviane F. Botosso
Nicholas D. Paola
Daniel F. L. Neto
Marielton P. Cunha
Carla T. Braconi
Rúbens P. S. Alves
Monica R. Jesus
Lennon R. Pereira
Stella R. Melo
Flávio S. Mesquita
Vanessa B. Silveira
Luciano M. Thomazelli
Silvana R. Favoretto
Franciane B. Almonfrey
Regina C. R. M. Abdulkader
Joel M. Gabrili
Denise V. Tambourgi
Sérgio F. Oliveira
Karla Prieto
Michael R. Wiley
Luís C. S. Ferreira
Marcos V. Silva
Gustavo F. Palacios
Paolo M. A. Zanotto
Edison L. Durigon
We followed the presence of Zika virus (ZIKV) in four healthy adults (two men and two women), for periods ranging from 78 to 298 days post symptom onset. The patients were evaluated regarding the presence of the virus in different body fluids (blood, saliva, urine and semen), development of immune responses (including antibodies, cytokines and chemokines), and virus genetic variation within samples collected from semen and urine during the infection course. The analysis was focused primarily on the two male patients who shed the virus for up to 158 days after the initial symptoms. ZIKV particles were detected in the spermat...
Source: Viruses - Category: Virology Authors: Danielle B. L. Oliveira Giuliana S. Durigon Érica A. Mendes Jason T. Ladner Robert Andreata-Santos Danielle B. Araujo Viviane F. Botosso Nicholas D. Paola Daniel F. L. Neto Marielton P. Cunha Carla T. Braconi R úbens P. S. Alves Monica R. Jesus Lennon R Tags: Article Source Type: research
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