An experimental test of the mutation-selection balance model for the maintenance of genetic variance in fitness components

We describe the underlying theory and use it to test the MSB model for three traits in Drosophila melanogaster. We find evidence for differences among traits, with MSB being sufficient to explain genetic variance in larval viability but not male mating success or female fecundity. Our results are consistent with balancing selection on sexual fitness components, and demonstrate the feasibility of rigorous statistical tests of the MSB model.

Source: Proceedings of the Royal Society B: Biological Sciences - November 7, 2018 Category: Biology Authors: Sharp, N. P., Agrawal, A. F. Tags: genetics, evolution Source Type: research