PTPN22 1858C > T polymorphism is associated with increased CD154 expression and higher CD4+ T cells percentage in rheumatoid arthritis patients

ConclusionThePTPN22 1858  T risk allele is associated with increased CD4+ T cells percentage and high mCD154 expression in RA patients, which could favor the pro‐inflammatory cytokine release and the establishment of the inflammatory response at the seropositive RA.

Source: Journal of Clinical Laboratory Analysis - November 6, 2018 Category: Laboratory Medicine Authors: Yeniley Ruiz ‐Noa, Jorge Hernández‐Bello, Mara A. Llamas‐Covarrubias, Claudia A. Palafox‐Sánchez, Edith Oregon‐Romero, Pedro Ernesto Sánchez‐Hernández, Maria Guadalupe Ramírez‐Dueñas, Isela Parra‐Rojas, Jose Francisco Muñoz� Tags: RESEARCH ARTICLE Source Type: research